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Notably, this reduction in systemic LPS was accompanied by a down-regulation of pro-inflammatory mediators (e.g., TLR4, NF-B, and IL-6) in the uterus, suggesting that butyrate can alleviate high-grain induced inflammation across the gut-uterus axis by fortifying the epithelial barrier 166

It also considers the overall health impact of the food

When you eat carbohydrates, your blood glucose rises, and your pancreas releases insulin to shuttle that glucose out of the bloodstream and into your cells for energy or storage

Brain (2018) 141(7):206682

Nausea that reduces appetite in a typical patient can become a tool for restriction in someone with anorexia nervosa