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It must be distinguished between a limited EP damage with relatively stable fragments, closed fracture lines or small defects, which result in no or a limited loss of nucleus tissue (injury type B2), from large defect with a virtual complete loss of NP tissue into the vertebral bone (type B3)

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83,99 The expression of antioxidant enzymes (SOD, CAT, and GPx) is largely controlled by the interaction of Nrf2 with the antioxidant response element

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