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26,59,60 SGLT2i has the potential to treat MASH through four main mechanisms: decreasing hepatic de novo lipogenesis by lowering insulin levels, increasing fatty acid -oxidation by stimulating glucagon secretion, suppressing glucose-induced oxidative stress, and inhibiting liver fibrosis by lowering transforming growth factor-beta levels

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Second, the addition of supplemental ingredients to your semaglutide formulation is often regulatory strategy, not medical strategy

Zepeda, R