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Therefore, we assessed the effect of Sorafenib, another SLC7A11-targeting ferroptosis inducer that has been used for liver cancer therapy in clinic, on Tamoxifen resistant ZR-75-1 cells in vitro and in vivo

Glutaminase activity is present in many other tissues in addition to the kidney, such as the liver, small intestine, and neurons where its role is nearly as significant as it is within the kidney tubule

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Industry standards suggest 1-3 times per week initially for 4-8 weeks, though these lack evidence basis