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Very rarely, highly minor, temporary localized bruising exactly at the precise venous injection site from the IV drip cannula (resolves rapidly and naturally in a few days)

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Although this first reported analgesic effect of a GLP-1 analogue was likely mediated by its local anti-inflammatory action, GLP-1R is also expressed in dorsal root ganglion (DRG) neurons [86] and therefore could directly act on nociceptive pain in OA DRG neurons endings are present in synovium [87]

These findings are based on the results of two recently published clinical trials

N-acetyl L-cysteine provides precursors for glutathione production, while cordyceps and gotu kola contribute to antioxidant activity and cellular health