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At the same time, A1AT can associate to lipid rafts on neutrophils membrane, where it can interact with disintegrin/metalloproteinase 17 (ADAM-17), a membrane protein that controls the shedding of FCRIIb (CD16b), an event a process that is necessary for neutrophils chemotaxis (35)

The finding established that the GSH redox cycle is the primary intracellular antioxidant defence system in endothelial cells against peroxide-mediated oxidative stress, and remains a foundational reference for endothelial oxidative stress research using GSH manipulation

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Selenium also works to protect the thyroid gland from oxidative stress (87, 88)

Severe blood-brain barrier disruption in cardioembolic stroke