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Although beneficial in tumor cells, GPX4 inhibition can also trigger ferroptosis-induced death of immune cells in the tumor microenvironment leading to ineffective antitumor response

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Viability was assessed by Zombie UV Fixable Viability Dye (BioLegend) and cytokine production was measured by intracellular cytokine staining after 3 h stimulation with PMA (50 ng ml 1 ) (BioGems) and ionomycin (1 g ml 1 ) (BioGems) in the presence of brefeldin A (1 g ml 1 ) (GolgiPlug, BD Biosciences)

Nevertheless, Dual-energy X-ray absorptiometry (DXA) results may not accurately reflect bone strength in individuals with type 2 diabetes

Tursi, S