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Helicobacter GGT has been shown to inhibit proliferation of T-lymphocytes, an effect that has been suggested to play a role in the immune escape by these bacteria 16,49

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However, statins have been reported to prevent the activation and proliferation of T cells interacting with agonistic anti-CD3 monoclonal antibody (mAb) or Staphylococcus aureus enterotoxin (SEB), an impact attributed to the deficiency of pathways regulated by small Ras-like GTPases in T-cell receptor (TCR) signaling for the former stimulus through lymphocyte function-associated antigen 1 (LFA-1) blockage [47, 48]

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In conclusion, fenugreek has potential health benefits for diabetic retinopathy, owing to its antioxidant and anti-inflammatory properties, in addition to its ability to stimulate insulin secretion