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In particular, the four convergent pathophysiological axes identified in this review include (i) TGF-/STAT6-based fibrosis-inflammation axis, (ii) immune dysregulation via Th2 bias and alarmins, (iii) microenvironmental fixation by ROS, and (iv) upstream regulation failure due to barrier disruption

In our study, the most treatment-persistent individuals after 1 and 2 years of follow-up were those in the insulin group (89.8% and 77.2%, respectively)

"I didn't want to be in the drug-creation business

Broccoli, kale, cabbage, and mustard all contain a group of plant compounds called glucosinolates

10.1016/j.jaci.2020.08.041 79 HerathH