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The anabolic effects are dose-dependent and tissue-nonspecific: IGF-1 LR3 activates PI3K/Akt and MAPK/ERK pathways in myocytes, adipocytes, chondrocytes, and hepatocytes simultaneously

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The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems

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