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Funding This study was supported by Peoples Livelihood Science and Technology Project of Hebei Province (20377714D), Natural Science Foundation of Hebei Province (H2019206707 and H2019206674), National key Research and Development program (2018YFC1002104)
MT-IIs activation of MC3R and MC4R in mesolimbic dopamine circuits , including the ventral tegmental area and nucleus accumbens and modulates dopamine release and dopamine receptor signalling in reward and motivation circuits
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These shifts may not be direct but could result from related changes in body weight, insulin resistance, and blood sugar
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![Melanotan II; [121062-08-6]](https://www.peptide.com/wp-content/uploads/2019/05/AAPPTEC_black.png)
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