new indications for glp-1 drugs Guidelines Type 2 Diabetes in 2025 Very important disclaimer: GLP-1 medications

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10.3389/fmicb.2022.1005842 88 WangH.LiuC.ZhaoY.GaoG

Attrubys approval was supported by positive results from the Phase III ATTRibute-CM, where the transthyretin stabilizer significantly reduced death and cardiovascular-related hospitalization, and improved quality of life

Drucker commented: GLP1 [drugs] have given us so many wonderful results, but tackling these very challenging brain disorders has been disappointing There was a hope that we would see some benefit, and we didnt. From the Alzheimers Drug Discovery Foundation (ADDF), Howard Fillit, MD, emphasized that even negative trials move the field forward, pointing to the need to target the broader pathobiology of Alzheimers and to consider preventive or combination approaches informed by biomarker profiles

Clinical Pharmacokinetics and Pharmacodynamics of Saxagliptin, a Dipeptidyl Peptidase-4 Inhibitor