The results of this landmark clinical trial were published in the New England Journal of Medicine 2021
This produces a senescent phenotype of skin cells, leads to the release of innate immune molecules, which trigger autoimmunity, and ultimately causes dysfunction and death of melanocytes
For most people, common symptoms like nausea, diarrhea, constipation, fatigue, or headaches are most noticeable in the first few weeks and improve significantly as the body adjusts, especially with gradual dose increases and practical side-effect management
Individual results vary, and no compounded product carries FDA approval or an FDA-reviewed efficacy claim of its own
At 10 mg/mL, 2 units equals 0.2 mg