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Following Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), PwO often experience significant declines in bone microarchitecture and strength, as measured by HR-pQCT [37, 38]

If cardiovascular concerns have kept you from exploring TRT, the evidence base has substantively changed

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however, results have been reassuring and consistent with what doctors expect from similar treatments

These effects typically peak during dose escalation periods and often diminish with continued use as physiological adaptation occurs