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In contrast, the GO@GSH-FA treatment ameliorated these pathological alterations, as evidenced by a reduction in the number and severity of degenerated, necrotic, and lost neurons

The most pronounced increase in the urinary carnitine concentration was observed following the intake of 1.5 g of carnitine, where the concentration rose from a baseline median of 40 M (IQR: 2099) to 292.2 M (IQR: 92629) at 24 h, and remaining elevated at 48 h (Figure 3C)

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Hydrophobic and basic residues at the P 2 position enhance the affinity for cleavage compared with acidic residues (Reference Power, Nongonierma and Jakeman94)