Further, oxidative damage to phospholipids can induce ferroptosis, as described earlier, which has now been directly linked to the induction of neuroinflammation ( Discussion Together, these studies examining oxidative stress, redox dysregulation, metabolic alterations, and neuroinflammation suggest that these processes are all not only involved in the pathogenesis of epilepsy, but fundamentally linked (See Scheme 1)
Strategies to optimize mitochondrial function could play an important role in limiting disease initiation and progress
Like RAASis, after an initial reversible hemodynamic dip in GFR, further loss of GFR was substantially reduced in the SGLT2i group [54]
These healthy changes naturally increase fluid intake and may affect urination patterns
Some GLP-1 medications may reduce thirst or fluid intake in certain patients, while eating less can also mean getting less water from food