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The observed reduction in NNT achieved by the inclusion of additional endpoints beyond the primary endpoint speaks to the limitations of a restricted definition of benefit

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In the fight against discrimination, as in the fight against obesity, we are in uncharted territory, the former FDA commissioner David Kessler writes about GLP-1 access in a recent book titled Diet, Drugs and Dopamine. One big exception to the coverage denial trend: For seniors, Medicare this month launched a pilot program that covers weight-loss drugs for just a $50 monthly copay