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Rats receiving brainstem-hypothalamic transection do not have a reduction in food intake in response to peripherally administered GLP-1 which suggests that the brainstem plays a critical role in communicating peripheral satiety signals to higher brain centers (Abbott et al., 2005)

If a household refrigerator is the only option, use a thermometer, keep the vial boxed, and avoid locations that freeze

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Inside mitochondria, energy is produced through a sequence of reactions known as the electron transport chain