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The copper ion component binds to fibroblast growth factor receptors, upregulating vascular endothelial growth factor (VEGF) expression in dermal papilla cells

[6] : 690 Medium-sized congenital melanocytic nevus is defined as having a diameter more than 2 cm (0.79 in) but less than 20 cm (7.9 in)

A qualified doctor or a nurse will then disinfect the skin over the injection area, which is often on your arm, locate a vein and insert an IV catheter