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Contraindication: Do not exceed the recommended dose

The mechanism involves iron overload suppressing the expression of bone formation-related transcription factors, including runt-related transcription factor 2 (RunX2), osteocalcin (OCN), and alkaline phosphatase (ALP), which subsequently reduces SLC7A11/GPX4 levels and ultimately induces ferroptosis (31)

Nucl Med Commun