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S100A8/A9: from basic science to clinical application

In various cancer cell lines, such as MDA-MB-231 human breast cancer, prostate cancer (PC3, DU145, LNCaP), and prognostic colon cancer (Ki-67) cells, cannabinoids have demonstrated the ability to downregulate key cell cycle regulatory proteins and inhibit cell cycle progression, leading to reduced cell proliferation [55,59,60,61]

One of the first things to understand is that our core body temperature is regulated by our brain (pituitary gland) and it works to our 24 hour circadian rhythm

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