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Downregulation of AKR1C3 leads to decreased YAP nuclear translocation, inhibiting the cystine transporter SLC7A11, thereby increasing intracellular ferrous iron levels and promoting ferroptosis (Chen et al., 2023)

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Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase