The early observational signals have not held up under closer review
Starting with an initial dose of 0.5 mg weekly allowed gradual dose escalation to the therapeutic dose of 1 mg weekly, minimizing the risk of adverse effects commonly associated with higher doses
We proposed to specify under new 425.600(h)(1)(iii) that an ACO determined to be inexperienced with performance-based risk Medicare ACO initiatives but which is not eligible to enter the BASIC track's glide path, in accordance with the provisions of 425.600(h)(1), may enter BASIC track Level E for all performance years of the agreement period, or the ENHANCED track, subject to the proposed exception prohibiting ACOs with fewer than 5,000 assigned beneficiaries in BY1, BY2, or both, from participating in the ENHANCED track specified in new 425.600(h)(3) (described in section III.F.4.b.(2).(b) of the CY 2026 PFS proposed rule)
We have to be very careful, as an industry, how we position these types of ingredients and how we manage consumer expectations, she says
2017;28:S47S56