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Diseases [edit] Oxidative stress is suspected to be important in neurodegenerative diseases including Lou Gehrig's disease (aka MND or ALS), Parkinson's disease, Alzheimer's disease, Huntington's disease, depression, multiple sclerosis and multiple system atrophy

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What this mechanism does NOT prove: Demonstrating a receptor interaction or pathway upregulation in rat tissue or cell culture does not confirm a clinically meaningful effect in humans at any given dose

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