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Determination of initial turnover number The initial turnover rates were determined in PBS at pH 7.4 (8 g l 1 NaCl (Labkem, SOCH-00T), 1.44 g l 1 Na 2 HPO 4 (Supelco, 1.06586), 0.2 g l 1 KCl (Panreac, 131494) and 0.24 g l 1 KH 2 PO 4 (Fisher Scientific, BP362)) using ABTS (1 mM), DMP (5 mM), guaiacol (50 mM), sinapic acid (0.35 mM) or p -coumaric acid (0.1 mM) as substrate

Methods: In vivo experiments, wild-type mice were fed western diet for 12 or 24 weeks to induce NASH

Estrella J, Correa A, Swisher SG , Ajani J, Rashid A, Hofstetter WL, Maru D

One major concern is ensuring that corporate or government entities dont misuse genetic information against consumers