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Key findings from the landmark STEP 1 clinical trial: ~15% Average body weight lost over 68 weeks (STEP 1 trial) 34 lbs Average weight lost by patients on semaglutide 2.4 mg 83% of semaglutide patients lost at least 5% of body weight vs

Prostate problems: Benign prostate hyperplasia (BPH) mostly affects older men

Nadolsky says that for some of his patients at the highest dose of tirzepatide, the drug is sometimes "dampening that dopamine reward system down so much that now, instead of just getting away from those addictive behaviors, they don't feel like doing anything." Some of those high-dose patients start seeking out sugar, not due to cravings, he says, but because their bodies are searching for some kind of stimulation to get the reward system going again

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AGEs-related dysfunctions in PCOS: evidence from animal and clinical research