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51,52 Although our preclinical studies mostly employed male mice, this choice was made to minimize variability, particularly because MAOB is located on the X chromosome, making males a more straightforward model for assessing MAOB effects without the potential confound of X-inactivation

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B cells in ASCVD B cells are highly dynamic regulators of atherosclerosis, influencing plaque development and progression through the secretion of cytokines and antibodies