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Reports most frequently included: nausea vomiting diarrhea Tirzepatide known by the brand-name Mounjaro, appears to be a safe and effective adjunct therapy to slow-release insulin in the treatment of uncontrolled diabetes

This paradoxical response reflects individual variation in how the gastrointestinal system responds to slowed gastric emptying and altered gut transit time

pregnancies are unplanned. Pregnancy an exclusion criteria in trials, but pregnancies still occurred The SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) clinical trial program, which led to the FDA approval of semaglutide for type 2 diabetes treatment, excluded women who were pregnant, breastfeeding or intending to become pregnant

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So far, data show tirzepatide reduces liver fat and improves cholesterol levels, factors that play important roles in heart health