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Compounded therapy options with adjustable dosing may reduce severity before chronic damage occurs

Some drugs that may interact with topiramate include other antiepileptic drugs, other carbonic anhydrase inhibitors, CNS depressants, estrogen-containing or progestin-only contraceptives, hydrochlorothiazide (HCTZ), diabetes drugs, lithium, amitriptyline, antihistamines, and alcohol

These effects result from delayed gastric emptying and are usually mild to moderate in severity

Further research on rotator cuff injuries demonstrated similar benefits

Some women lose only a few pounds, while others lose 10 pounds or more over several months