Neurological symptoms are among the most clinically significant and may include: Tingling, numbness, or a 'pins and needles' sensation in the hands and feet Difficulty with balance and coordination (sensory ataxia) Memory problems, cognitive slowing, or confusion Mood changes, including low mood or irritability Haematological symptoms may include: Persistent fatigue and weakness Breathlessness on exertion Pallor or a slightly yellowish tinge to the skin A sore, inflamed tongue (glossitis) It is worth emphasising that neurological damage from B12 deficiency including subacute combined degeneration of the spinal cord can progress and become irreversible if treatment is delayed, even in cases where anaemia is absent
Experts say that while the findings are promising, more research is still needed
The evidence describes the compound class, not what any single person will experience on a given protocol
Zou X, Huang Q, Luo Y, et al
The potential nephroprotective mechanisms of GLP-1RAs likely involve GLP-1RA-mediated improvements of conventional risk factors for diabetic kidney disease (control of glycaemia, postprandial lipid level, body weight and blood pressure), but perhaps also direct effects on the kidneys
01053-X/asset/826330f0-5581-4d6d-8f45-2192fe6ac242/main.assets/gr2_lrg.jpg)
