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The results of pharmacokinetic analyses performed in normal volunteers show that following 4 mg SC, a peak plasma level 3 ng/mL (2.4 nmol/L) was obtained with a terminal half-life of 20 min (21)

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BAMM (BRAF autophagy and MEK inhibition in melanoma): A phase I/II trial of dabrafenib, trametinib, and hydroxychloroquine in advanced BRAFV600-mutant melanoma