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Lithium activates neuroprotective pathways including GSK-3 inhibition, enhanced autophagy, and synaptic resilience, while also modulating inflammation and tau phosphorylation

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Long-term treatment must be considered in addition to short-term medicines, taking into account the potential consequences of the artificial tears, anti-inflammatory eye drops, and punctal plugs are examples of conventional treatments for dry eye disease that can be successful, but long-term use can be costly and may result in adverse effects that limit patient adherence [38, 39]

Other employers may limit treatment duration unless employees achieve specific health benchmarks , like a 5% weight reduction within six months