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Samenius proposed that MC is more frequently observed in patients with an obstruction anywhere in the colon and rectum than in cases of chronic constipation where there is no mechanical cause for the constipation.8 A list of the etiologies of MC is shown in Fig

Additionally, the excessive reduction of cystine to cysteine consumes large amounts of NADPH, a critical cofactor for maintaining cellular reducing power (Chandel, 2021) (Figure 8)

From bugs to brain: unravelling the GABA signalling networks in the braingutmicrobiome axis

Isolation and identification of urinary metabolites of berberine in rats and humans