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A 6-month, randomized, double-masked, placebo-controlled study evaluating the effects of the protein kinase C-beta inhibitor ruboxistaurin on skin microvascular blood flow and other measures of diabetic peripheral neuropathy

First, due to the lack of detailed individual information regarding sex, mental and physical conditions, and other concomitant diseases, subgroups that may show more beneficial effects of antioxidants could not be selected (Lu et al., 2022)

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Additionally, a link between add-on GLP-1 receptor agonists and even fewer asthma attacks was reported in this population, according to researchers