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6.2 Linking GSH/GSSG to Transcriptomic and Proteomic Regulation Transcriptomic and proteomic data can connect metabolite changes to functional modules: GCLC/GCLM/GSS for synthesis, SLC7A11 for substrate acquisition, GSR/GPX/GST for regeneration and use, pentose phosphate pathway enzymes for NADPH supply, and NRF2-KEAP1 signaling for coordinated antioxidant adaptation

Losing muscle can slow metabolism, reduce functional strength, and impede sustained weight management

Elevated levels of homocysteine in the blood, known as hyperhomocysteinemia, have been linked to an increased risk of cardiovascular disease, including heart attack and stroke

ketoconazole, diltiazem) or inducers (e.g

Efficacy and safety of the novel dipeptidyl peptidase-4 inhibitor gemigliptin in the management of type 2 diabetes: A meta-analysis