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This is a process where unstable molecules called free radicals cause damage to your cellular structures

[55] It does this by upregulating phosphorylated IRS-1 and activating pathways (like AMPK/SIRT1) that promote the transport of the GLUT4 glucose transporter to cell membranes in muscle and adipose tissue, thereby increasing overall cellular glucose uptake

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As we received feedback during the development of the model that the magnitude of upside adjustments would need to be meaningful to engender the practice transformations that ASM aims to achieve, we believe that using an approach that creates a consistent incentive for all ASM participants to continually improve performance on the required measures and attestations is preferable