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A summary of approximate phases, based on trial data, is as follows: Weeks 14: Appetite suppression and early metabolic changes may begin Weeks 412: Noticeable weight loss may commence Weeks 1248+: Progressive weight reduction, continuing through the trial period at higher doses These timelines reflect phase 2 trial experience and may differ in real-world settings

- April 23, 2025 - AM-PR The extensive body of research from Mayo Clinic emphasizes major advancements in obesity, including prediction of GLP-1 side effects, a new obesity sub-phenotype, and insights into personalized bariatric and endoscopic procedures

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