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At present this has been utilised predominantly in graft versus host disease after hematopoietic stem cell transplantation [45]

Decreases food intake reduces how much food is eaten Increases insulin sensitivity helping the body release insulin when blood sugar is high Enhances first and second phase insulin secretion helps the body remove excess sugar from the blood Slows gastric emptying slows down how quickly food leaves the stomach (this will lessen over time) Reduces glucagon levels stops the liver from making and releasing too much sugar

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Trettel, J., Fortin, D

PROs were assessed at baseline, endpoint (week 52) and any early discontinuation visit using the instruments described below