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Cancer Metastasis Rev 38(12):205222 Rajeshkumar NV, Yabuuchi S, Pai SG et al (2017) Treatment of pancreatic cancer patient-derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin

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Figure 1 5 Cognitive dysfunction linked to intestinal I/R injury and BBB compromise During intestinal ischemiareperfusion (I/R) injury, the intestinal barrier integrity breaks compromised and puts in motion a cascade of events that might ultimately influence cognitive function