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Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling

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In addition, Pycnogenol increased the total antioxidant status (TAS) and improved the glutathione levels, another index for antioxidant capacity in the children with ADHD ( administration, while reduced glutathione (GSH) was significantly increased by 26.8% after one month and by 36.4% after 2 months compared to baseline ( s effects on ADHD symptoms by improving the antioxidant status