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Description

Furthermore, introducing lactic acid in the process of DCs differentiation in vitro led to a phenotype similar to that of tumor-associated dendritic cells (TADCs) formed within melanoma and prostate carcinoma MCTSs, marked by inhibited differentiation and reduced IL-12 secretion

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Limitations of the study is study shows results from a cell culture experiment

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Xu X, Chen C, Lu W-J, et al

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GSTO1 has been shown to play a significant role in the protein glutathionylation cycle exhibiting both glutathionylation and deglutathionylation activities 11,15

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