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Interestingly, 78c showed no activity against ADP-ribosyl cyclase at concentrations up to 50 nM, while it exhibited no modulatory effects on CD157, suggesting its specificity toward CD38 139

Early laboratory studies show that GLP-1 agonists like exendin-4 can slow the growth of breast cancer cells and increase programmed cell death, and a 2025 mouse study found that tirzepatide slowed the growth of obesity associated breast tumors

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In this video, we Learn more What if We're Using GLP-1 Medications All Wrong