Clinical studies demonstrate minimal impact on cortisol levels (unlike GHRP-6 and GHRP-2), negligible prolactin elevation, and no significant effects on FSH, LH, TSH, or ACTH at therapeutic dosages
This peptide works in the following ways: Activates ghrelin receptors Triggers the release of growth hormone Mimicks the bodys natural hunger pathways While there are many peptides that may be used with CJC-1295, heres what makes Ipamorelin unique: It does not significantly increase cortisol Has minimal impact on prolactin Highly targeted towards growth hormone stimulation Because of its uniqueness and minimal effect on other hormones, Ipamorelin is also called a clean peptide compared to older GHRPs like GHRP-6
Serum GH and IGF-1 measurements tell the real story, and those measurements consistently favor nocturnal timing across populations
In animals (rats, pigs, dogs), ipamorelin does not raise ACTH or cortisol at doses up to 200 its GH-release ED (Raun 1998)
Better overall skin texture 4
