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It can also cause loose stools in some individuals, and has undesirable filler ingredients like polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone, sodium lauryl sulfate, synthetic black iron oxides, and titanium dioxide

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doi: 10.1007/s11064-018-2679-4

Because of the functional differences in HCV proteins, genetic variation in some parts of the genome confers advantages by evading or inhibiting the host immune system, whereas other mutations may be lethal to the virus if they lead to defective replication machinery

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