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Here we review recent developments and challenges related to selected bloodbrain barrier-crossing strategies with a focus on non-invasive approaches such as receptor-mediated transcytosis and the use of neurotropic viruses, nanoparticles and exosomes and analyse their potential in the treatment of CNS disorders

BPC-157 for GERD Acid Reflux Research: Preclinical Evidence Base The most cited study on BPC-157 and gastric protection comes from a 2020 paper in Frontiers in Pharmacology , which found the peptide reduced gastric acid hypersecretion induced by pentagastrin in rats while simultaneously protecting against mucosal damage from NSAIDs

Tirzepatide is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and should not be used during pregnancy due to potential fetal harm

After demonstrating that SYNCRIP enhances SIRT1 expression and attenuates ferroptosis, we investigated the molecular mechanisms underlying this regulation

Association of neurosurgical resection with development of pachymeningeal seeding in patients with brain metastases