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2g, indirect effect = 0.813, bootstrap standard error [SE] = 0.344, P = 0.018), suggesting that disrupted neurovascular coupling may underlie PTSD pathology

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This results in the activation of mast cells and the release of inflammatory mediators, including histamine, leukotrienes, and others, which can manifest as pruritus, urticaria, angioedema, bronchospasm, vomiting, and hypotension

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