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Therefore, present result indicates that GSTP1 AA-genotype has stronger affinity to JNK as compared with the mutant which might impair c-Jun-phosphorylation and reduce the extent of apoptosis

USA 104 , 23312336 (2007)

This has been demonstrated in the development of several clinical candidates and approved drugs 26,27,28,29

The 3-adrenergic receptor is particularly abundant in adipose tissue and is a key regulator of lipolysis and thermogenesis, making it an ideal target for fat-reducing interventions