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Researchers conducted a randomized, double-blind, placebo-controlled trial comparing the effects of placebo , L-citrulline (2g) , glutathione (1g) , and the combination of L-citrulline (2g) with glutathione (200mg)

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Thus, if the GSH:GSSG ratio remains unchanged, decreases in glutathione concentration in themselves cause the redox potential to increase, ie, become more positive (Figure 7)

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