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Semaglutide does not require drug level monitoring but does require regular monitoring of blood glucose and sometimes kidney function depending on the patient

Physicians who were familiar with peptide therapy as recently as 2022 may be working from outdated information about legal availability

In addition, conditions such as pregnancy, eating disorders, pancreatitis history, cardiovascular disease, and substance use disorders may affect which medications are safe to use

However, recent evidence suggests that non-12-OH FXR-antagonistic BAs in humans exert similar metabolic effects observed for those non-12-OH FXR-antagonistic BAs in rodents 29