Clinical studies and meta-analyses suggest that ALA supplementation can lead to small but meaningful improvements in fasting glucose and insulin sensitivity, particularly in people with type 2 diabetes or metabolic syndrome.2 24 That said, these effects are generally modest and ALA should never be viewed as a substitute for prescribed diabetes medications
Considering that GLP-1R agonists are FDA approved drugs to treat T2DM and also ameliorate NASH, in the present study we evaluated the efficacy of a GLP-1R agonist in two mouse models: one model with NASH-like features (methionine and choline-deficient (MCD) diet), and a second high-fat model of metabolic syndrome and hepatic dysfunction
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This makes 4 servings